VAMP3 (8A3) Monoclonal Antibody
Product Specifications
Background
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP3 is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. VAMP3 is involved in vesicular transport from the late endosomes to the trans-Golgi network.
Synonyms
Vesicle-associated membrane protein 3; Cellubrevin; Synaptobrevin-3; VAMP-3; CEB; SYB3
Gene ID
9341
Swiss Prot
Q15836
Cellular Locus
Cytoplasm, Membrane bound
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
VAMP3
Clonality
Monoclonal
Isotype
IgG
Clone
8A3
Conjugation
Unconjugated
Source
Synthetic peptide conjugated to KLH within N-terminal human VAMP3/Cellubrevin.
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
9341
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