Oct-1 Recombinant Antibody
Product Specifications
Background
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Synonyms
POU domain class 2 transcription factor 1; NF-A1; Octamer-binding protein 1; Octamer-binding transcription factor 1; Oct-1; OTF-1; POU2F1; OCT1; OTF1
Gene ID
5451
Swiss Prot
P14859
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Oct-1
Clonality
Monoclonal
Isotype
IgG
Clone
1C14
Conjugation
Unconjugated
Source
Recombinant protein within human POU2F1 aa 1-150.
Applications
WB, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
5451
Curated Selection
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