CREB1 (Ser133) (5F2) Monoclonal Antibody
Product Specifications
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Synonyms
Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1; CREB1; Phospho-Creb1; p-Creb1
Gene ID
1385
Swiss Prot
P16220
Modification Site
Ser133
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
CREB1 (Ser133)
Clonality
Monoclonal
Isotype
IgG
Clone
5F2
Conjugation
Unconjugated
Source
Synthetic phospho-peptide corresponding to residues surrounding Ser133 of human Creb
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
1385
Curated Selection
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