Cytochrome P450 Oxidoreductase (4F7) Monoclonal Antibody
Selected Variant
bsm-54281R
Size: 100 µL
Product Specifications
Background
Cytochrome P450 Oxidoreductase is an endoplasmic reticulum membrane oxidoreductase with a FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Synonyms
NADPH cytochrome P450 reductase; CPR; P450R; POR; CYPOR; Cytochrome p450 Reductase
Gene ID
5447
Swiss Prot
P16435
Cellular Locus
Endoplasmic reticulum
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
POR
Clonality
Monoclonal
Isotype
IgG
Clone
4F7
Conjugation
Unconjugated
Source
Recombinant protein within human Cytochrome P450 Reductase aa 1-150
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
5447
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC941877-500 1x 500 µL
Cytokeratin, Multi (Epithelial Marker) (KRT/1877R), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882117-100 1x 100 µL
ARF1 (Golgi Apparatus Marker) (ARF1/2117), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
A13464-Dylight550 100 µg
Anti-SDF2L1 Antibody Picoband®, Dylight550 Conjugate
Sign In for Pricing
View Details 
BNCB1783-500 1x 500 µL
CD45RB (B-Cell Marker) (PTPRC/1783R), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042646-500 1x 500 µL
CD73 (Immuno-Oncology Target) (NT5E/2646), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details