Cytochrome P450 Oxidoreductase (4F7) Monoclonal Antibody
Product Specifications
Background
Cytochrome P450 Oxidoreductase is an endoplasmic reticulum membrane oxidoreductase with a FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Synonyms
NADPH cytochrome P450 reductase; CPR; P450R; POR; CYPOR; Cytochrome p450 Reductase
Gene ID
5447
Swiss Prot
P16435
Cellular Locus
Endoplasmic reticulum
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
POR
Clonality
Monoclonal
Isotype
IgG
Clone
4F7
Conjugation
Unconjugated
Source
Recombinant protein within human Cytochrome P450 Reductase aa 1-150
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
5447
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15311115 1 Vial
Lentiviral human KLK4 shRNA (UAS) - Lentiviral human KLK4 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details KL1-C5269-100ug 100 µg
Cynomolgus KLRG1 Protein, Fc Tag (SPR verified)
Sign In for Pricing
View Details QY-E11924 96 Tests
Rat SH3 and multiple ankyrin repeat domains protein 1 (SHANK1) ELISA Kit
Sign In for Pricing
View Details