GORASP1 (3G1) Monoclonal Antibody
Product Specifications
Background
Plays an important role in assembly and membrane stacking of the Golgi cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes. Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane
Synonyms
Golgi reassembly stacking protein 1; Golgi peripheral membrane protein p65; Golgi phosphoprotein 5; Golgi reassembly-stacking protein of 65 kDa; GOLPH5; GRASP65; GORASP1; GRASP65.
Gene ID
64689
Swiss Prot
Q9BQQ3
Cellular Locus
Golgi apparatus
Host
Rabbit
Cross Reactivity
Human
Target
GORASP1
Clonality
Monoclonal
Isotype
IgG
Clone
3G1
Conjugation
Unconjugated
Source
Recombinant protein within human GRASP65 aa 300-440
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
64689
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