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GORASP1 (3G1) Monoclonal Antibody

Product Specifications

Background

Plays an important role in assembly and membrane stacking of the Golgi cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes. Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane

Synonyms

Golgi reassembly stacking protein 1; Golgi peripheral membrane protein p65; Golgi phosphoprotein 5; Golgi reassembly-stacking protein of 65 kDa; GOLPH5; GRASP65; GORASP1; GRASP65.

Gene ID

64689

Swiss Prot

Q9BQQ3

Cellular Locus

Golgi apparatus

Host

Rabbit

Cross Reactivity

Human

Target

GORASP1

Clonality

Monoclonal

Isotype

IgG

Clone

3G1

Conjugation

Unconjugated

Source

Recombinant protein within human GRASP65 aa 300-440

Applications

WB, FCM, IHC-P, IF (IHC-P), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

64689

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