HNRNPU (1F6) Monoclonal Antibody
Product Specifications
Background
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are thought to be involved in pre-mRNA processing. However, its role in the regulation of gene expression is as yet poorly understood. Proteins of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally diverse group of RNA binding proteins implicated in various functions. Recently, hnRNP proteins have been shown to hinder communication between factors bound to different splice sites. Conversely, several reports have described a positive role for some hnRNP proteins in pre-mRNA splicing. hnRNP-U, also termed scaffold attachment factor A (SAF-A), binds to pre-mRNA and nuclear matrix/scaffold attachment region DNA elements.
Synonyms
Heterogeneous nuclear ribonucleoprotein U; GRIP120; Nuclear p120 ribonucleoprotein; Scaffold-attachment factor A; p120; pp120; hnRNP U; SAF-A; HNRNPU; C1orf199; HNRPU; SAFA; U21.1
Gene ID
3192
Swiss Prot
Q00839
Cellular Locus
Nucleus, Cytoskeleton
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
HNRNPU
Clonality
Monoclonal
Isotype
IgG
Clone
1F6
Conjugation
Unconjugated
Source
Recombinant protein within human hnRNP U aa 1-150
Applications
WB, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
3192
Curated Selection
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