PSD93/DLG2 Recombinant Antibody
Product Specifications
Background
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. DLG2 is required for the perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in the regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
Synonyms
Disks large homolog 2; Channel-associated protein of synapse-110; Postsynaptic density protein PSD-93; Chapsyn-110; DLG2; discs large MAGUK scaffold protein 2; PSD93; PPP1R58
Gene ID
1740
Swiss Prot
Q15700
Host
Rabbit
Cross Reactivity
Human
Target
PSD93/DLG2
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant protein within human PSD93 aa 600-870
Applications
WB, FCM, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
1740
Predicted Cross Reactivity
Mouse, Rat
Available Sizes
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