Alpha 1 Antichymotrypsin (9D4) Monoclonal Antibody
Product Specifications
Background
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains.
Synonyms
Alpha-1-antichymotrypsin, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, ACT, SERPINA3, AACT, GIG24, GIG25
Gene ID
12
Swiss Prot
P01011
Host
Rabbit
Cross Reactivity
Human
Target
SERPINA3
Clonality
Monoclonal
Isotype
IgG
Clone
9D4
Conjugation
Unconjugated
Source
Full length protein
Applications
WB, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
12
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