Insulin Receptor R (8A1) Monoclonal Antibody
Product Specifications
Background
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Synonyms
Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, IRR, INSRR
Gene ID
3645
Swiss Prot
P14616
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
INSRR
Clonality
Monoclonal
Isotype
IgG
Clone
8A1
Conjugation
Unconjugated
Source
N terminal Human Insulin Receptor R
Applications
WB, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
3645
Curated Selection
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