ITPR1 (5G10) Monoclonal Antibody
Product Specifications
Background
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity) .
Synonyms
Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1; IP3 Receptor.
Gene ID
3708
Swiss Prot
Q14643
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
ITPR1
Clonality
Monoclonal
Isotype
IgG
Clone
5G10
Conjugation
Unconjugated
Source
Human IP3 receptor aa 1770-1900
Applications
IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment.
Gene ID URL
3708
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