MGluR1 (2C1) Monoclonal Antibody
Product Specifications
Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
Synonyms
Metabotropic glutamate receptor 1, mGluR1, GRM1
Gene ID
2911
Swiss Prot
Q13255
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
MGluR1
Clonality
Monoclonal
Isotype
IgG
Clone
2C1
Conjugation
Unconjugated
Source
Human mGluR1 between 100-300 amino acids
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2911
Curated Selection
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