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MGluR1 (2C1) Monoclonal Antibody

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

Synonyms

Metabotropic glutamate receptor 1, mGluR1, GRM1

Gene ID

2911

Swiss Prot

Q13255

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

MGluR1

Clonality

Monoclonal

Isotype

IgG

Clone

2C1

Conjugation

Unconjugated

Source

Human mGluR1 between 100-300 amino acids

Applications

WB, IHC-P, IF (IHC-P)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

2911

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