FMRP (1B6) Monoclonal Antibody
Product Specifications
Background
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity) . RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly (G), binds moderately to poly (U) but shows very little binding to poly (A) or poly (C) .
Synonyms
Synaptic functional regulator FMR1, Fragile X mental retardation protein 1, FMRP, Protein FMR-1, FMR1
Gene ID
2332
Swiss Prot
Q06787
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
FMRP
Clonality
Monoclonal
Isotype
IgG
Clone
1B6
Conjugation
Unconjugated
Source
Human FMRP aa 1-100
Applications
WB, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2332
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NB100-66385AF350 0.1 mL
Mouse Monoclonal Alkaline Phosphatase, Liver/Bone/Kidney Antibody (BGN/03/662) [Alexa Fluor 350]
Ask
View Details MBS7246710-01 48 Well
Bovine Cutaneous T-cell lymphoma-associated antigen 5 (CTAGE5) ELISA Kit
Ask
View Details 
MBS7246710-02 96 Well
Bovine Cutaneous T-cell lymphoma-associated antigen 5 (CTAGE5) ELISA Kit
Ask
View Details