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Src (8C4) Monoclonal Antibody

Product Specifications

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC

Gene ID

6714

Swiss Prot

P12931

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Src

Clonality

Monoclonal

Isotype

IgG

Clone

8C4

Conjugation

Unconjugated

Source

Human Src between 1 to 100 amino acids

Applications

WB, FCM, IHC-P, IF (ICC), IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

6714

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