Insulin degrading enzyme (3C9) Monoclonal Antibody
Product Specifications
Background
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Synonyms
Insulin-degrading enzyme, Abeta-degrading protease, Insulin protease, Insulysin, Insulinase, IDE
Gene ID
3416
Swiss Prot
P14735
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat, Zebrafish
Target
Insulin degrading enzyme
Clonality
Monoclonal
Isotype
IgG
Clone
3C9
Conjugation
Unconjugated
Source
Human Insulin degrading enzyme aa 950 to the C-terminus
Applications
WB, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3416
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