SHP2 (8A1F) Monoclonal Antibody
Product Specifications
Background
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
Synonyms
Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, PTP-1D, PTP-2C, SHP-2, Shp2, PTPN11, PTP2C, SHPTP2
Gene ID
5781
Swiss Prot
Q06124
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
SHP2
Clonality
Monoclonal
Isotype
IgG
Clone
8A1F
Conjugation
Unconjugated
Source
SHP2 between 200 to 550 amino acids
Applications
WB, IHC-P, IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
5781
Curated Selection
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