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F11R/JAM-A/CD321 Recombinant Antibody

Product Specifications

Background

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Synonyms

Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD321; JAM-A; JAMA; JAM-1; JAM1; PAM-1; F11R

Gene ID

50848

Swiss Prot

Q9Y624

Cellular Locus

Cell membrane, Extracellular domain, Cell junction

Host

Rabbit

Cross Reactivity

Human

Target

F11R/JAM-A/CD321

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

Human Junctional Adhesion Molecule 1 between 28-241 amino acids

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

50848

Predicted Cross Reactivity

Mouse, Rat

Available Sizes

Frequently Asked Questions

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