Integrin linked ILK (3G2) Monoclonal Antibody
Product Specifications
Background
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Synonyms
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK
Gene ID
3611
Swiss Prot
Q13418
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Integrin linked ILK
Clonality
Monoclonal
Isotype
IgG
Clone
3G2
Conjugation
Unconjugated
Source
Recombinant protein within Human Integrin linked ILK between 400 amino acids to the C-terminus
Applications
WB, FCM, IHC-P, IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3611
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