EIF5A (3A6) Monoclonal Antibody
Product Specifications
Background
MRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Synonyms
Eukaryotic translation initiation factor 5A-1, Eukaryotic initiation factor 5A isoform 1, Rev-binding factor, eIF-4D, eIF-5A-1, eIF-5A1, eIF-5A, EIF5A
Gene ID
1984
Swiss Prot
P63241
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
EIF5A
Clonality
Monoclonal
Isotype
IgG
Clone
3A6
Conjugation
Unconjugated
Source
Recombinant protein within Human eIF5A between 50-150 amino acids
Applications
WB, FCM, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
1984
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
