GSK3 beta (1C8) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Synonyms
Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B, GSK3B
Gene ID
2932
Swiss Prot
P49841
Cellular Locus
Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
GSK3 beta
Clonality
Monoclonal
Isotype
IgG
Clone
1C8
Conjugation
Unconjugated
Source
Recombinant human GSK3 beta between 350 amino acids to C-terminus
Applications
WB, FCM, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2932
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