Topoisomerase II alpha (3F10) Monoclonal Antibody
Product Specifications
Background
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .
Synonyms
DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme, TOP2A, TOP2
Gene ID
7153
Swiss Prot
P11388
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Topoisomerase II alpha
Clonality
Monoclonal
Isotype
IgG
Clone
3F10
Conjugation
Unconjugated
Source
Recombinant human Topoisomerase II beta between 50 to 150 amino acids
Applications
WB, IHC-P, IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
7153
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