NADPH oxidase 4 Recombinant Antibody, HRP Conjugated
Product Specifications
Background
Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Synonyms
NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD (P) H-oxidase, KOX-1, NOX4, RENOX
Gene ID
50507
Swiss Prot
Q9NPH5
Host
Rabbit
Cross Reactivity
Human, Rat
Target
NADPH oxidase 4
Clonality
Monoclonal
Isotype
IgG
Clone
2A4
Conjugation
HRP
Source
Recombinant human NADPH oxidase 4 between 500 to C-terminus
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
50507
Predicted Cross Reactivity
Mouse
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