Apaf-1 (4G2) Monoclonal Antibody
Product Specifications
Background
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Synonyms
Apoptotic protease-activating factor 1, APAF-1, APAF1
Gene ID
317
Swiss Prot
O14727
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Apaf-1
Clonality
Monoclonal
Isotype
IgG
Clone
4G2
Conjugation
Unconjugated
Source
Recombinant human Apaf-1 between 1 to 300 amino acids
Applications
WB, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
317
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