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VEGFR1 Recombinant Antibody

Product Specifications

Background

VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.

Synonyms

Vascular endothelial growth factor receptor 1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor, VEGFR-1, FLT-1, FLT, FLT1

Gene ID

2321

Swiss Prot

P17948

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

VEGFR1

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

Recombinant protein

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

2321

Available Sizes

Curated Selection

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