EIF-2a (Ser51) Monoclonal Antibody

Product Specifications

Background

Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

Synonyms

Eukaryotic translation initiation factor 2A, 65 kDa eukaryotic translation initiation factor 2A, EIF2A, CDA02, MSTP004, MSTP089

Gene ID

83939

Swiss Prot

Q9BY44

Modification Site

Ser51

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

EIF-2a (Ser51)

Clonality

Monoclonal

Isotype

IgG

Clone

8B5

Conjugation

Unconjugated

Source

Synthetic phospho-peptide surrounding Ser51 of human eIF-2a

Applications

WB, FCM, IHC-P, IF (ICC), IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

83939

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