Caveolin-1 (9C11) Monoclonal Antibody
Product Specifications
Background
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity) . Involved in the costimulatory signal essential for T-cell receptor (TCR) -mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Synonyms
Caveolin-1; CAV1; CAV
Gene ID
857
Swiss Prot
Q03135
Cellular Locus
Cell membrane, Golgi apparatus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
CAV1
Clonality
Monoclonal
Isotype
IgG
Clone
9C11
Conjugation
Unconjugated
Source
Human Caveolin-1 aa 100-250
Applications
WB, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
857
Curated Selection
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