ARPC5 Recombinant Antibody
Product Specifications
Background
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079) . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947) . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) .
Synonyms
Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5
Gene ID
10092
Swiss Prot
O15511
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
1-50/151
Target
ARPC5
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant human p16 ARC around N-terminus
Applications
WB, FCM, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
10092
Predicted Cross Reactivity
Rat
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx432944 200 µL
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 (LYVE1) Antibody
Sign In for Pricing
View Details 
MBS6267198-01 0.1 mL
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) (BSA & Azide Free) (MaxLight 405)
Sign In for Pricing
View Details MBS6267198-02 5x 0.1 mL
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) (BSA & Azide Free) (MaxLight 405)
Sign In for Pricing
View Details