Histone H3 (mono+di+methyl K79) (2B11) Monoclonal Antibody
Product Specifications
Background
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Synonyms
Histone H3, Histone H3
Swiss Prot
P68431
Modification Site
Mono+di+methyl K79
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Histone H3 (mono+di+methyl K79)
Clonality
Monoclonal
Isotype
IgG
Clone
2B11
Conjugation
Unconjugated
Source
Synthetic peptide surrounding K79 of Histone H3
Applications
WB, FCM, IHC-P, IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Methylation
Storage Conditions
Store at -20°C for 12 months.
Curated Selection
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