Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
Histone H2A.1, Histone H2A.2, Histone H2A type 1-B/E, Histone H2A type 1-C, Histone H2A type 1-J, Histone H2A/e, Histone H2A/l, H2A2, HIST1H2AB, HIST1H2AC, HIST1H2AJ; Histone H2A.2; Histone H2A/a; Histone H2A/m
Gene ID
3012; 8335
Swiss Prot
P04908
Modification Site
Hydroxyl Y39
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Histone H2A (hydroxyl Y39)
Clonality
Monoclonal
Isotype
IgG
Clone
2A3
Conjugation
Unconjugated
Source
Synthetic peptide surrounding Y39 of Histone H2A
Applications
WB, IHC-P, IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Methylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3012; 8335
Curated Selection
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