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Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone H2A.1, Histone H2A.2, Histone H2A type 1-B/E, Histone H2A type 1-C, Histone H2A type 1-J, Histone H2A/e, Histone H2A/l, H2A2, HIST1H2AB, HIST1H2AC, HIST1H2AJ; Histone H2A.2; Histone H2A/a; Histone H2A/m

Gene ID

3012; 8335

Swiss Prot

P04908

Modification Site

Hydroxyl Y39

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Histone H2A (hydroxyl Y39)

Clonality

Monoclonal

Isotype

IgG

Clone

2A3

Conjugation

Unconjugated

Source

Synthetic peptide surrounding Y39 of Histone H2A

Applications

WB, IHC-P, IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Methylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

3012; 8335

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