Caspase 2 (2B1) Monoclonal Antibody
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.
Synonyms
Caspase-2; Neural precursor cell expressed developmentally down-regulated protein 2; Protease ICH-1; CASP-2; NEDD-2; Caspase-2 subunit p18
Gene ID
835
Swiss Prot
P42575
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
CASP2
Clonality
Monoclonal
Isotype
IgG
Clone
2B1
Conjugation
Unconjugated
Source
Recombinant human Caspase-2 between 150 to 350 amino acids
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
835
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