PUMA (2G6) Monoclonal Antibody
Product Specifications
Background
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (PubMed:11463391) . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis (PubMed:23340338) .
Synonyms
Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3
Gene ID
27113
Swiss Prot
Q9BXH1
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
PUMA
Clonality
Monoclonal
Isotype
IgG
Clone
2G6
Conjugation
Unconjugated
Source
Human PUMA from 150 amino acids to the C-terminus
Applications
WB, FCM, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
27113
Curated Selection
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