DLG4 (1H8) Monoclonal Antibody
Product Specifications
Background
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity) .
Synonyms
Disks large homolog 4; Postsynaptic density protein 95; Synapse-associated protein 90; PSD-95; SAP-90; SAP90; Disks large homolog 4; discs large MAGUK scaffold protein 4; DLG4
Gene ID
1742
Swiss Prot
P78352
Cellular Locus
Cell membrane, Cell junction
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
DLG4
Clonality
Monoclonal
Isotype
IgG
Clone
1H8
Conjugation
Unconjugated
Source
Recombinant human PSD95 around N-terminus
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
1742
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
