Phospho-Histone H1.3 (T17) +Histone H1.4 (T17) (3A4) Monoclonal Antibody
Product Specifications
Background
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) .
Synonyms
Histone H1.3, Histone H1c, Histone H1s-2, Histone H1.4, Histone H1b, Histone H1s-4, HIST1H1D, HIST1H1E
Swiss Prot
P10412
Modification Site
T17+Histone H1.4
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Histone H1.3 (T17) +Histone H1.4 (T17)
Clonality
Monoclonal
Isotype
IgG
Clone
3A4
Conjugation
Unconjugated
Source
Synthetic phospho-peptide around Thr17 of human H1.4
Applications
WB, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
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