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PBR (1D4) Monoclonal Antibody

Product Specifications

Background

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity) . Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678) .

Synonyms

Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR, TSPO

Gene ID

706

Swiss Prot

P30536

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

PBR

Clonality

Monoclonal

Isotype

IgG

Clone

1D4

Conjugation

Unconjugated

Source

Human PBP between 50-150 amino acids

Applications

WB, FCM, IHC-P, IF (ICC), IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

706

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