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CREB (2B5) Monoclonal Antibody

Product Specifications

Background

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Synonyms

Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1

Swiss Prot

P16220

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Zebrafish

Target

CREB

Clonality

Monoclonal

Isotype

IgG

Clone

2B5

Conjugation

Unconjugated

Source

Human CREB from 50 to 200 amino acids

Applications

WB, FCM, IHC-P, IF (ICC), IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

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