CREB (2B5) Monoclonal Antibody
Product Specifications
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Synonyms
Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1
Swiss Prot
P16220
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat, Zebrafish
Target
CREB
Clonality
Monoclonal
Isotype
IgG
Clone
2B5
Conjugation
Unconjugated
Source
Human CREB from 50 to 200 amino acids
Applications
WB, FCM, IHC-P, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
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