HDAC8 Recombinant Antibody

Product Specifications

Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Synonyms

HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1; Histone deacetylase 8; HDAC8

Gene ID

55869

Swiss Prot

Q9BY41

Host

Rabbit

Cross Reactivity

Human

Target

HDAC8

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

Recombinant human HDAC8 protein, around N-terminal 150aa.

Applications

WB, Flow-Cyt, ICC/IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

55869

Available Sizes

Curated Selection

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