Cytokeratin 4 Recombinant Antibody
Product Specifications
Background
Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
Synonyms
Keratin, type II cytoskeletal 4; KRT4
Gene ID
3851
Swiss Prot
P19013
Host
Rabbit
Cross Reactivity
Rat
Target
Cytokeratin 4
Clonality
Recombinant
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant human Cytokeratin 4 protein, around 350-480aa.
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3851
Predicted Cross Reactivity
Human
Available Sizes
Curated Selection
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