CD10 Monoclonal Antibody
Product Specifications
Background
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Synonyms
MME; NEP; NEP_HUMAN; Atriopeptidase; CALLA; CD 10; CD10; Common acute lymphocytic leukemia antigen; DKFZp686O16152; EC 3.4.24.11; Enkephalinase; EPN; gp100; Membrane metallo endopeptidase; Membrane metalloendopeptidase; Membrane metalloendopeptidase neutral endopeptidase enkephalinase; Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10; Membrane metalloendopeptidase variant 1; Membrane metalloendopeptidase variant 2; MGC126681; MGC126707; Neprilysin; Neutral endopeptidase 24.11; Neutral endopeptidase; Neprilysin; Skin fibroblast elastase; SFE.
Gene ID
4311
Swiss Prot
P08473
Cellular Locus
Cell membrane
Host
Mouse
Cross Reactivity
Human
Immunogen
401-550/750
Target
CD10
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
B4S1
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CD10
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
WB (WB (1:500-2000) ), IHC-P (IHC-P (1:100-500) ), IHC-F (IHC-F (1:100-500) ), IF (IF (1:100-500) )
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4311
Curated Selection
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