XIAP Monoclonal Antibody

Product Specifications

Background

Apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. Inhibitor of caspase-3, -7 and -9. Mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B.

Synonyms

X-linked Inhibitor of Apoptosis Protein; RIAP-3; Baculoviral IAP repeat-containing protein 4; E3 ubiquitin-protein ligase XIAP; Inhibitor of apoptosis protein 3; X-linked IAP; IAP-like protein; HILP; BIRC4; HILP; XLP2; ILP1; Xiap; MIHA; hILP; IAP3; API3; XIAP_HUMAN; ILP; hILP; IAP-3; hIAP-3; hIAP3; X-linked inhibitor of apoptosis protein.

Gene ID

331

Swiss Prot

P98170

Cellular Locus

Cytoplasm

Host

Mouse

Cross Reactivity

Human

Target

XIAP

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

D1G6

Conjugation

Unconjugated

Source

Recombinant human XIAP.

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein G.

Concentration

0.5µg/µl

Dilution

WB (WB (1:500-4000) ), IHC-P (IHC-P (1:20-100) ), IHC-F (IHC-F (1:20-100) ), IF (IF (1:20-100) )

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

331

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