BCL10 Monoclonal Antibody
Product Specifications
Background
Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
Synonyms
Bcl-10; B cell CLL/lymphoma 10; B cell lymphoma/leukemia10; B-cell leukemia/lymphoma 10; Bcl 10; c E10; c-E10; C81403; CARD containing apoptotic signaling protein; CARD containing molecule enhancing NF kappa B; CARD containing molecule enhancing NF kB; CARD containing molecule enhancing NFkB; CARD containing proapoptotic protein; CARD like apoptotic protein; CARMEN; Caspase recruiting domain containing protein; cCARMEN; cE 10; cE10; CED 3/ICH 1 prodomain homologous E10 like regulator; CED3/ICH1 prodomain homologous E10 like regulator; Cellular E10; Cellular homolog of vCARMEN; CIPER; CLAP; hCLAP; Mammalian CARD containing adapter molecule E10; mE 10; mE10; R-RCD1; BCL10_HUMAN.
Gene ID
8915
Swiss Prot
O95999
Cellular Locus
Cytoplasm, Cell membrane
Host
Mouse
Cross Reactivity
Human
Immunogen
1-130/233
Target
BCL10
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
G56
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human BCL10
Applications
WB, IHC-P, IHC-F, IF, Flow-Cyt
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
WB (WB (1:500-2000) ), IHC-P (IHC-P (1:100-500) ), IHC-F (IHC-F (1:100-500) ), IF (IF (1:100-500) ), Flow-Cyt (Flow-Cyt (1:50-100) )
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8915
Predicted Cross Reactivity
Human
Curated Selection
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