UCHL1/PGP9.5 Monoclonal Antibody
Product Specifications
Background
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Synonyms
Gracile axonal dystrophy; Neuron cytoplasmic protein 9.5; Park 5; Park5; Parkinson Disease 5; PGP 9.5; PGP95; Protein gene product 9.5; Ubiquitin C terminal esterase L1; Ubiquitin C terminal hydrolase (neuron specific) ; Ubiquitin C terminal hydrolase; Ubiquitin carboxyl terminal esterase L1; Ubiquitin carboxyl terminal hydrolase isozyme L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin thioesterase L1; Ubiquitin thiolesterase; Ubiquitin thiolesterase L1; UCH L1; UCH-L1; UCHL1; UCHL1_HUMAN.
Gene ID
7345
Swiss Prot
P09936
Cellular Locus
Cytoplasm, Cell membrane
Host
Mouse
Cross Reactivity
Xenopus laevis
Immunogen
151-223/223
Target
UCHL1/PGP9.5
Clonality
Monoclonal
Isotype
IgG1
Clone
T2F5
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human UCHL1/PGP9.5
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-1000), IHC-P (IHC-P=1:20-50), IHC-F (IHC-F=1:400-800), IF (IF=1:100-500)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
7345
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Pig, Monkey
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