BCL10 (5C2) Monoclonal Antibody
Product Specifications
Background
Involved in adaptive immune response (PubMed:25365219) . Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101) .
Synonyms
CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; Mammalian CARD-containing adapter molecule E10; BCL10
Gene ID
8915
Swiss Prot
O95999
Host
Mouse
Cross Reactivity
Human
Target
BCL10
Clonality
Monoclonal
Isotype
IgG1
Clone
5C2
Conjugation
Unconjugated
Source
This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10.
Applications
WB, FCM, IHC-P, IF
Purification
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8915
Curated Selection
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