E cadherin Monoclonal Antibody
Product Specifications
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Synonyms
UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
Gene ID
999
Swiss Prot
P12830
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Immunogen
1-392/882
Target
E cadherin
Clonality
Monoclonal
Isotype
IgG1
Clone
9C8
Conjugation
Unconjugated
Source
This CADH1 antibody is generated from a mouse immunized with a recombinat protein between 1-392 amino acids from human CADH1.
Applications
IHC-P, IHC-F, IF
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
999
Predicted Cross Reactivity
Monkey
Curated Selection
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