BANP (4C2) Monoclonal Antibody
Product Specifications
Background
Controls V (D) J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity) .
Synonyms
BEND1; SMAR1; SMARBP1; Protein BANP; BEN domain-containing protein 1; Btg3-associated nuclear protein; Scaffold/matrix-associated region-1-binding protein; BANP
Gene ID
54971
Swiss Prot
Q8N9N5
Host
Mouse
Cross Reactivity
Human
Target
BANP
Clonality
Monoclonal
Isotype
IgG1
Clone
4C2
Conjugation
Unconjugated
Source
This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.
Applications
WB, IHC-P
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
54971
Curated Selection
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