DENR (2C9) Monoclonal Antibody
Product Specifications
Background
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Synonyms
DRP; DRP1; SMAP-3; Density-regulated protein; Protein DRP1; Smooth muscle cell-associated protein 3; DENR; H14
Gene ID
8562
Swiss Prot
O43583
Host
Mouse
Cross Reactivity
Human
Target
DENR
Clonality
Monoclonal
Isotype
IgG2b
Clone
2C9
Conjugation
Unconjugated
Source
This DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.
Applications
WB, FCM, IHC-P, IF (ICC), IF
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8562
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