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DENR (2C9) Monoclonal Antibody

Product Specifications

Background

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Synonyms

DRP; DRP1; SMAP-3; Density-regulated protein; Protein DRP1; Smooth muscle cell-associated protein 3; DENR; H14

Gene ID

8562

Swiss Prot

O43583

Host

Mouse

Cross Reactivity

Human

Target

DENR

Clonality

Monoclonal

Isotype

IgG2b

Clone

2C9

Conjugation

Unconjugated

Source

This DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.

Applications

WB, FCM, IHC-P, IF (ICC), IF

Purification

Purified by Protein G.

Concentration

0.5µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (ICC) (1:50-200), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

8562

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