CDKN1B (10B7) Monoclonal Antibody
Product Specifications
Background
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Synonyms
KIP1; MEN4; CDKN4; MEN1B; P27KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; CDKN1B
Gene ID
1027
Swiss Prot
P46527
Host
Mouse
Cross Reactivity
Human
Target
CDKN1B
Clonality
Monoclonal
Isotype
IgG1
Clone
10B7
Conjugation
Unconjugated
Source
This CDKN1B antibody is generated from a mouse immunized with CDKN1B recombinant protein.
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein G.
Concentration
0.5µg/µl
Dilution
WB (WB=1:500-1000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:20-200), IF (IF=1:20-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
1027
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