ITA6 (9C5) Monoclonal Antibody
Product Specifications
Background
Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity) . ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778) . ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760) .
Synonyms
CD49f; VLA-6; ITGA6B; Integrin alpha-6; CD49 antigen-like family member F; ITGA6
Gene ID
3655
Swiss Prot
P23229
Host
Mouse
Cross Reactivity
Human
Target
ITA6
Clonality
Monoclonal
Isotype
IgG1
Clone
9C5
Conjugation
Unconjugated
Source
ITA6 recombinant protein is used to produce this monoclonal antibody.
Applications
WB, FCM, IHC-P, IF
Purification
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Concentration
0.5µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
3655
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