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Osteocalcin Monoclonal Antibody

Product Specifications

Background

Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.

Synonyms

Osteocalcin Propeptide; Gamma-carboxyglutamic acid-containing protein; Bone Gla-protein; BGLAP; Bone gamma carboxyglutamate protein; BGLAP; BGP; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gla protein; Gamma carboxyglutamic acid containing protein; OC; PMF1; OSTCN_HUMAN.

Gene ID

632

Swiss Prot

P02818

Host

Mouse

Cross Reactivity

Human

Target

Osteocalcin

Clonality

Monoclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Recombinant human Osteocalcin protein

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

1mg/ml

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

632

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