Collagen II Monoclonal Antibody, Biotin Conjugated
Product Specifications
Background
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
Collagen II alpha 1; COL2A1; COL2A1 protein; collagen, type II, alpha 1; collagen alpha-1 (II) ; type II collagen; alpha-1 type II collagen; alpha1 type II collagen; Col2a1; AOM; Cartilage collagen; Chondrocalcin; COL11A3; Collagen alpha 1 (II) chain precursor; Collagen II alpha 1 polypeptide; Collagen type II alpha 1 (primary osteoarthritis spondyloepiphyseal dysplasia congenital) ; MGC131516; SEDC; Collagen alpha-1 (II) chain; Alpha-1 type II collagen; CO2A1_HUMAN.
Gene ID
1280
Swiss Prot
P02458
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Immunogen
1301-1400/1487
Target
Collagen II
Clonality
Monoclonal
Isotype
IgG
Clone
9H12
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Collagen II
Applications
IHC-P, IHC-F
Purification
Purified by Protein G.
Concentration
1µg/µl
Dilution
IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
1280
Curated Selection
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